Endocrine
Perspective
by
GEOFFREY P. REDMOND, M.D.
Past Endocrine Columns
Rumors
that my new book really is coming out at last are true. The title is The
Hormonally Vulnerable Woman and it is published by ReganBooks/HarperCollins.
As the many of you who are my friends know, I have been planning this for a long
time. My earlier book, The Good News About Women’s Hormones came out in
1995 and there have been many developments in women’s health in the intervening
ten years. Also, I have seen several thousand more women in my practice and as
always, I have learned much from them. Indeed, I dedicated this latest book to
my patients who have been my greatest teachers. I have also acknowledged my
wife, Mingmei Yip, for keeping me cheerful, almost, during the arduous process
of writing this new book.
The title and theme of
hormonal vulnerability reflects my growing awareness of how pervasive the
effects of hormones are on a women’s well-being. Often tests are normal, but
appearance, physical well-being and emotions are adversely affected. The
problem, I have come to realize, is that many women’s bodies over-react to
normal levels of their own hormones. This is certainly the case with hirsutism.
I remember when I first became interested in this problem I saw a woman who had
to shave twice a day. I am sure all electrologists have seen other unlucky women
with this problem. In her case, as in many others, testosterone levels were
normal. Other doctors had told her she was normal, based on her tests, but as
she put it to me, “For a woman to have to shave is not normal.” She was right,
of course.
In an earlier column I
explained some of the reasons a testosterone result can be normal in such
situations. What I emphasize in The Hormonally Vulnerable Woman is that
most often, the problem is not the hormones themselves but how an individual
woman’s body reacts to them. This is what I term hormonal vulnerability. Of
course, sometimes hormone levels are abnormal, making matters even worse.
When I wrote The
Good News About Women’s Hormones, I was upfront about the problems women
have getting help for almost any sort of hormonal condition. Electrologists are
well aware of this with regard to hirsutism. I’d hoped that things would quickly
improve but am sorry to say that in the ten years since that book, things are
only slightly better. There is, for example, much greater awareness of
polycystic ovary syndrome (PCOS) but full understanding is not yet easily found.
My purpose in writing
The Hormonally Vulnerable Woman was to give women the information they
need to understand their hormones and get help. I cover not only the skin and
hair problems caused by testosterone – acne, hirsutism and alopecia – but also
other common conditions such as PMS, mood swings, metabolic effects of PCOS, and
menopause. As always, I do my best to show how hormone problems can be overcome
with treatments available today. The treatment of PCOS has been transformed by
the introduction of metformin (Glucophage). Yet metformin is not, as some
doctors assume, a cure-all for PCOS. Antiandrogens are still necessary for
control of acne, hirsutism and alopecia. In the new book, I’ve tried to bring
out these subtleties in the treatment of PCOS.
Menopause and hormone
replacement, always fraught subjects, have only gotten more so. In the new book,
I’ve explained that hormone therapy with estrogen is not in itself good or bad
but rather good for some women and bad for others. I offer a series of
guidelines to help women make a decision which will be comfortable for them.
An area I cover much
more extensively in The Hormonally Vulnerable Woman than in my previous
book is sexual difficulties, particularly loss of interest. Recent studies show
that about a third of women feel their libido is lower than they would like.
When I’ve lectured to electrologists I’m always asked about this, so they are no
more immune than any other group of women.
The use of
testosterone has been widely publicized as a way for women to enhance their
desire. In the past I have been very critical of this trend because I see so
many women who have been given excessive doses that put their levels in the male
range. The result, not surprisingly, is hair loss, hirsutism and acne. I’ve even
seen a few women whose doctors told them that testosterone would help their
alopecia. I’ve spoken out against this sort of endocrine abuse, at times
annoying those who perpetuate it.
Recently however,
results of the testosterone patch studies have been published and indicate that
problems are infrequent, providing that only enough testosterone is used to give
blood levels that are appropriate for a woman. I’ve even devised a method for
doing so, which I describe in detail in The Hormonally Vulnerable Woman.
I feel the future of testosterone therapy for women lies in teaching doctors how
to correctly dose and monitor it. The women’s testosterone patch, Intrinsa, will
be a great step forward when it is finally approved. In the meantime, safe use
is possible with the method described in my book. Nonetheless, women with
hirsutism or other testosterone-related problems should be very hesitant about
taking testosterone in any form.
I strive to give a
message of hope. So many women with hormonal vulnerability end up demoralized,
their lives on hold, because no one seems able to help. As medicine becomes more
complex, better treatments are available but become harder to find. By using the
information I provide in The Hormonally Vulnerable Woman, readers will be
empowered to seek the treatments that can solve their problems.
Past Endocrine Columns